Background: Hashimoto's thyroiditis has been found to coexist with differentiated thyroid cancer in surgical specimens, but an association between the two conditions has been discounted by the medical literature. So, we performed this research to determine any potential relationship between Hashimoto's thyroiditis and the risk of developing differentiated thyroid cancer in clinical status. we assessed the related clinical factors linking these conditions, especially serum thyroid-stimulating hormone concentration, family history of thyroid disease, gender& young age group. Aim of study: to determine that hashimoto’s thyroiditis increases risk for differentiated thyroid carcinoma. Patients and method: This study is a Cross-sectional study carried out in surgical ward of Baghdad teaching hospital, where 82 patients followed up for one year from 1/10/2017 to 1/10/2018. Clinical history and examination with thyroid function tests, ultrasound and FNAC done for them pre operatively, post-operatively all thyroid specimen sent for histopathological study. Results: Differentiated thyroid cancer with Hashimoto's thyroiditis patients: (84.6%) had papillary thyroid cancer with Mean age of patients is 37.3±3.3 and Female gender represents 92.3% of differentiated thyroid cancer with Hashimoto's thyroiditis patients. About 53.8%of differentiated thyroid cancer with Hashimoto's thyroiditis patients had high thyroid-stimulating hormone at presentation. About 61.5% of differentiated thyroid cancer with Hashimoto's thyroiditis patients had positive family history of thyroid disease. Most our patients had multinodular goiter 80.5%, only 19.5% had single nodule, in Differentiated thyroid cancer with Hashimoto's thyroiditis patients (papillary thyroid cancer: 81.8% multinodular goiter and18.2% Single nodule, while all Follicular Thyroid Cancer patients had multinodular goiter).Fine needle aspiration biopsy in diagnosis of Hashimoto's thyroiditis pre-operation had Sensitivity 61% & specificity98%.
Background: The estimation of ferritin and related variables by complete serum iron profile, for Iraqi hashimoto’s patients to see the effect of thyroid hormone insufficiency, which may lead to deficiency of ferritin iron stores, this may be quite useful during the diagnosis and treatment of hashimoto’s patients. Patients and Method: The study was performed at National Center of Teaching laboratories of Medical city institute in Baghdad. Fifty newly diagnosed patients with hashimoto’s and forty apparently healthy controls. Diagnosis based on thyroid profile analysis including:Thyroid Stimulating Hormone (TSH), Thyroxine (totalT4) and Triiodothyronine (total T3), estimation of antibodies against thyroperoxidase, iron profile including:
... Show More
(2)
(5)
Background: The occurrence of incidental thyroid cancer (ITC) has increased by three times during the last decades and this rise could be attributed to many factors. To limit the prevalence of ITC with goiter especially nodular goiter, total thyroidectomy can become a procedure of choice.
Objective: To determine the extent of incidental thyroid carcinoma (ITC) and to plan a proper preoperative diagnostic work up and a convenient operative procedure for patients with different thyroid diseases.
Results: ITC was found in 77 patients (19.15%). While, 63 patients with non-toxic MNG (15.6%), 12 patients with non-toxic solitary thyroid nodule (3%) and two patients (0.5%) wi
(1)
Background: thyroid carcinoma is the most common endocrine carcinoma as it accounts for almost 90% of all endocrine malignancies. The term incidental denoted malignant tumors of the thyroid gland detected by post-operative biopsy results of the resected specimens resected from benign thyroid diseases. Among the incidental thyroid malignancies, papillary carcinoma is the commonest pathological type.
Objectives : To determine the incidence of incidental thyroid carcinoma and to insist on accurate preoperative diagnostic work up of patients with thyroid diseases.
Patients & Methods: A prospective study, which was conducted during the period from March 2013 to April 2014 at Baghdad teaching hospital first surgical unit by the same
BACKGROUND: Papillary thyroid carcinoma (PTC) is the most common type of thyroid carcinoma that represents a set of characteristic of nuclear features in which the diagnosis is depend. AIM: The study aimed to review different variants of PTC which has different malignant potential in correlation with many prognostic and clinical factors in Iraq. PATIENTS AND METHODS: Paraffin blocks of 227 cases of PTC were selected, subtyped, and grouped according to the malignant potential. The prognostic and clinical factors were studied. RESULTS: The mean age was (39.29 ± 12.17) years, with female predominance (86.3%), where (55.5%) of them below 40 years, conventional variant was most common (40.1%), followed by papillary microcarcinoma
... Show More
(2)
(2)
(1)
Background: Papillary thyroid carcinoma (PTC) is the commonest thyroid cancer. Cases in category-
5a of Bethesda system (suspicious for papillary carcinoma) are treated by surgical lobectomy followed
by total thyroidectomy if histopathology confirms papillary carcinoma. In order to reduce surgical
procedures to one this was conducted.
Objectives: evaluation of role of immunohistochemistry in pre-operative diagnosis of papillary thyroid
carcinoma on cell blocks.
Materials and Method: Cell blocks were taken from cases labelled category-5a for histopathology and
immunohistochemistry using three markers (CK-19, Thyro-peroxidase, and BRAFv600E mutation).
Results: were highly sensitive, and specific. The use of more tha
Background: Hypocalcaemia is a well-recognized complication of thyroid surgery. It is the most often transient event that occurs after extensive thyroid resection that may require calcium and/or vitamin D supplements to alleviate or prevent the symptoms.
Objective: of this study is to determine the incidence of hypocalcaemia after thyroid surgery and find out the risk factors involved regarding the patient age, gender, and muscular build, clinical diagnosis, the extent of surgery, ligation of the inferior thyroid artery, pathology report and the experience of the surgeon.
Patients and methods: This prospective study was carried out on 100 patients who underwent thyroid surgery for
Background: Population studies suggest that 3–8% of asymptomatic adults have thyroid nodules. Nodules have a 5–15% prevalence of malignancy. Fine-needle aspiration cytology is the primary and frequently initial tool for assessing the risk of malignancy in thyroid nodules and selecting patients for thyroid surgery.
Patients and Methods: This prospective study was done during the period from June 2007 to November 2008. The study includes 141 patients with palpable solitary or multiple thyroid nodules. Only patients with normal or low TSH values were referred for ultrasound examination and ultrasound guided FNAC, which were done using fine needles (G 20).
Results: eleven patients (7.8%) have insuffici
Thyroid cancer is a rare malignancy with wide interethnic and geographic variations (l).it constitutes 1% of solid organ malignancy (2) but they are still the most common endocrine (3)cancer .well differentiated (follicular and papillary thyroid carcinoma accounts for 80-90% of the approximately 28000 new cases each year and the estimate of 376000 existing cases of primary thyroid cancer in Europe and united states(2) , while in Germany it is the 13th most frequent maiignancy(2-7) new cases per 100000 inhabitantsK 1)-
There have been many recent advances in our understanding of thyroid diseases. An adenoma- carcii.oma sequence for the development of thyroid neoplasm has been based on the characterization of a number proto-oncogene and