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The research work was conducted to investigate the effect of oral administration
of water extract of black pepper at doses of (1, 5) mg/kg body weight for two weeks
daily by determining the genotoxic effect (mitotic index), evaluation of
immunological effect (IgG, IgM, IgA, C3, C4) and measuring fertility hormones
(follicles stimulation hormone/FSH, lutenising hormone/LH) levels with
histopathological examinations of female albino swiss mice ovaries in comparison
with control (normal saline). A clear effect in increasing mitotic activity was reveled
for both doses in comparison with control. Results also showed a significant
increase in the value of the all immunological parameters at both doses in
comparison with control. Also obvious rais
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