Objectives: This study explored knowledge, attitude, and practice of infection control by dental students at College of Dentistry/ University of Baghdad, Iraq. Material and Methods: Three hundred dental students participated in this study. A self administrated questionnaire with 21 close ended questions related to use of personal protective equipments, infection control awareness, vaccination status, percutaneous exposures, and attitude towards treatment of patients with hepatitis B (HBV)/ or human immunodeficiency virus (HIV) was distributed to dental students. Data were analyzed using Statistical Package for Social Sciences (SPSS) version 21. Fisher exact and Chi-square test were used with significance level set to 0.05. Results: The response rate was high (92%). The majority of students received hepatitis B vaccine (undergraduates 84.04% and postgraduates 91.11%). Needle stick injuries was the most common type for percutanuous injuries with larger number of injuries occurred among postgraduates (85.56%) in comparison to (55.85%) in undergraduates (p < 0.05). Majority of students used personal protective equipments, but only a small proportion of them washed their hands before donating gloves. There was a significant difference (P = 0.021) between undergraduates (15.96%) and postgraduates (27.78%) attitude towards treatment of patient with history of HBV or HIV. Conclusion: More efforts must be spent to improve students' attitude and compliance with infection control policy. Also, a continuous and rigorous assessment of students’ knowledge and practice of infection control measure must be done to ensure that the best is delivered by our dental students while treating their patients.