CYTOKINES PROFILE FOR INTESTINAL AND SPLEEN HOMOGENATE
FOR IMMUNOSUPPRESSANT BALB/C MICE INFECTED WITH
CRYPTOSPORIDIUM PARVUM
Cryptosporidium parvum
intestinal and spleen homogenate
IFN-g
TNF-a
Cryptosporidiosis is mainly cause a persistent diarrhea in immune compromised patients, BALB/c mice have been suppressed by dexamethasone, tissue Th1, Th2 and Th17 cytokines concentrations in the ileum were significantly diminished in both infected and immunosuppressed mice. Level of IFN-g, TNF-a, IL-12, IL-6, IL-17A was increased in level, IL-4 didn’t increases, in both ileal and spleen tissue. Levels of above cytokines were examined in spleen in order to follow the proliferation of CD4+ T-cell during C. parvum infection.
