ABSTRACT: BACKGROUND: Infantile haemangioma one of the most common tumour of new borns , a safe and effective treatment options are under ongoing research . OBJECTIVE: The authors show the effectiveness and safety of low dose propranolol as a method for infantile haemangioma treatment . METHOD: In this study twenty- four patients with infantile haemangioma in different anatomical locations were treated with oral propranolol and the result were assessed in a retrospective analysis of the results patients were kept on 0.25 mg/kg/day for one month , then on 0.5mg/kg/day in 2 divided doses for another one month , in the third month the dose will be increased to 1 mg/kg/day in 2 divided doses , then the propranolol were given in a maintenance dose ranging between 1-1.5 mg/kg/day in 2 divided doses according to the clinical response .The duration of treatment ranging from 6-18 months as a small dose increasing over a long time . RESULTS: We had achieved excellent result in most of our patients, with reduction of size and fade of color of hemangioma within 1 month from the initiation of treatment, when we stop the treatment no relapses were noticed during our follow up period after finishing the course. CONCLUSION: Propranolol is one of the safest and most effective treatment options for the infantile haemangioma even in low dose, with lower relapse rates and minimal consecutive side effects and drawbacks. KEYWORDS: propranolol, infantile, haemangioma
Type 2 diabetes mellitus (T2DM) is a potentially fatal metabolic disorder worldwide, in this COVID-19 era. Long-term allopathic treatment has a variety of side effects, prompting the search for alternative therapies. Oleuropein, the primary bioactive ingredient of Olive Leaf Extract (OLE), has shown noteworthy actions to control T2DM. The present study provides a dynamic study of % improvement in GLUT4 concentration with different doses of metformin (150mg-500mg) in combination with 500mg using a dynamic in silico model developed in Cell Designer 4.4.2, a system biology tool. The results indicated that 300mg of metformin and 500mg of oleuropein is the optimum combination to treat diabetes, ensuring a 2% improvement in G
... Show MoreTotal no. of patient (100) stool samples were collected, during the period from February to the end of May of 2008, for children under two years old suffering from non-bloody and bloody diarrhea at (Children Welfare Teaching Hospital) in Baghdad. The study evaluates the relationship between etiological agent of diarrhea and sex, age group, type of feeding, presence of blood in stool of the patients. All samples were examined microscopically to identify parasitic agent and serological test for Rotavirus to identify viral infection, also biochemical and serological tested for specimen's culture on different culture media and antibiotic sensitivity test. Results show from 100 cases 64] represents the etiological agent of diarrhea and
... Show MoreBackground: Infantile hypertrophic pyloric
stenosis affects 0.5 – 3.0 per 1000 live birth and it is
the most common surgical cause of vomiting in
infancy.
Objective: To analyze variable peri-natal factors
that may be involved in the etiology of infantile
hypertrophic pyloric stenosis.
Methods: Over a two year's period, from January
2000 – December 2001, 31 cases of infantile
hypertrophic pyloric stenosis were evaluated for
variable peri-natal risk factors in AL-Eskan central
child teaching hospital for children.
Results: The 31 cases studied were 77.4% males
and 48.4% at three weeks of age. And of all cases,
51.6% were breast fed with a blood group (O) being
the predominant in 54.8%.
No
Let M be a n-dimensional manifold. A C1- map f : M M is called transversal if for all m N the graph of fm intersect transversally the diagonal of MM at each point (x,x) such that x is fixed point of fm. We study the minimal set of periods of f(M per (f)), where M has the same homology of the complex projective space and the real projective space. For maps of degree one we study the more general case of (M per (f)) for the class of continuous self-maps, where M has the same homology of the n-dimensional sphere.
Propranolol is a nonselective-adrenergic blocker used in the treatment of hypertension, cardiac arrhythmias, and angina pectoris. A significant problem in propranolol therapy is that it undergoes extensive presystemic metabolism after oral administration leading to reduced bioavailability. In this study, two new propranolol derivatives have been designed, synthesized and characterized. These compounds were formed by acylation of propranolol followed by nucleophilic substitution reaction of acylated propranolol, these derivatives were analyzed for IR, CHN, melting points, and evaluated for their lipophilic properties compared with propranolol. The lower partition coefficient of these two derivatives revealed that the prodrug approach may be
... Show MoreThe operator ψ has been introduced as an associated set-valued set function. Although it has importance for the study of minimal open sets as well as minimal I-open sets. As a result of this study, we introduce minimal I^*-open sets . In this study, several characterizations of minimal I^*-open sets are also investigated. This study also discusses the role of minimal I^*-open sets in the *-locally finite spaces. In an aspect of topological invariant, the homeomorphic images of minimal I^*-open set has been discussed here.
Background: Sclerotherapy is a simple treatment modality for treatment of infantile hemangioma and slow-flow vascular malformations; Polidocanol is a mild sclerosing agent that is traditionally used in treatment of varicose veins. This study aims to evaluate the effectiveness, treatment outcome, and complications of polidocanol foam sclerotherapy for infantile hemangioma and slow-flow vascular malformations. Materials and methods: Between March 2013 and December 2014, seventeen patients with infantile hemangioma and slow-flow vascular malformations treated with polidocanol 1% foam sclerotherapy. Foam was prepared by Tessari’s method. Injection performed under general or local anesthesia, injections were repeated (if necessary) on mon
... Show MoreBackground Median sternotomy is the gold standard incision for most cardiac operations. However, with the advent of minimal invasive surgery, a new approach emerged in cardiac surgery named mini-sternotomy and has been successfully used to perform a variety of operations.
The aim of this paper is to present our experience of using mini-sternotomy to harvest the left internal mammary artery (LIMA) for off-pump revascularization of the left anterior descending artery (LAD)
Methodology Over a 2-year period (October 2012-October 2014), 100 patients underwent coronary artery bypass grafting (CABG) via conventional median sternotomy (CMS) (n=80) and mini-sternotomy (MS) (n=20). The
... Show More
Student dropout is a problem for both students and universities. However, in the crises that Lebanon is going through, it is becoming a serious financial problem for Lebanese private universities. To try to minimize it, it must be predicted in order to implement the appropriate actions. In this paper, a method to build the appropriate prediction system is presented. First, it generates a data source of predictor variables from student dataset collected from a faculty of economic sciences in Beirut between 2010 and 2020. Then, it will build a prediction model using data classification techniques based on identified predictor variables and validate it. Using open-source software and free cloud environments, a prediction program w
... Show MoreIn this paper we introduced many new concepts all of these concepts completely
depended on the concept of feebly open set. The main concepts which introduced in
this paper are minimal f-open and maximal f-open sets. Also new types of
topological spaces introduced which called Tf min and Tf max spaces. Besides,
we present a package of maps called: minimal f-continuous, maximal f-continuous,
f-irresolute minimal, f-irresolute maximal, minimal f-irresolute and maximal firresolute.
Additionally we investigated some fundamental properties of the concepts
which presented in this paper.