This study was carried out in epidemically field with common reed (Phragmites communis Trin.) plants in the Nassiriah cityThiQur governorate ,during 2009/2010 to investigate the influence of plant growth regulator gibberellin (GA3)and cytokinin (CK) in increasing the efficacy of glyphosate and Fluazifop-butyl in common reed control . Factorial experiment in RCBD was used with three replications in tow Factors . Glyphosate 3500mg .l־¹ gave the higher mean of injury score of common reed and lower mean of common reed shoots , shoots dry weight and rhizome dry weight(3.59,22.01 shoot /0.5m² ,0.57Kg / 0.5m² and 250.50gm /0,5m² ),respectively. All plant growth regulators gaves the higher means of common reed shoots and rhizome dry weight compared with untreated control, GA3 1500mg.l־¹ gave preceded significantly in common reed shoots and rhizome dry weight (25,95shoot/0.5m²,357.75gm/0.5m²) respectively . Add of plant growth regulators cause in increasing the efficacy of herbicides in influence of common reed plants , and application of GA31500mg.l־¹ with glyphosate 3500mg.l־¹ gave higher mean of in jury score of common reed and decrease of shoots dry weight (4.10 ,0.48 Kg 0.5m² ) , respectively