Crabs belong to the crustacean family (Decapods crustacean), and their shells contain natural ingredients from which the bioactive compounds are derived. It has been used as folklore medicine in cancer treatment. We investigate the possible anti-inflammatory and anti-oxidant effects for crab shells and whole crabs. Thirty-six rats (150–200 gm) from both sexes were used, divided into six groups, the anti-inflammatory and anti-oxidant activity measured using cotton pellet induce granuloma model. Detection of tumor necrosis factor alpha (TNF α), Interleukin 1 beta (IL-1β), superoxide (SOD), and malondialdehyde (MDA) levels using ELISA Kits. The data analysis by one-way ANOVA followed by the Tukey test. Values are significant at (p < 0.05). The results and conclusion showed that the crude material for both crab shell and whole crab have anti-inflammatory and anti-oxidant activity with ELISA analysis.
Evaluation of the Anti-inflammatory and Anti-oxidant Activity of
Crab Components and Crab Shell in Experimental Rats in Comparison
with Dexamethasone and Diclofenac Sodium
Cotton pellet induced granuloma
Crab
Crab shell
Inflammation
Interleukin 1Beta (IL-1B)
Malodialdehyde (MDA)
Superoxide dismutase (SOD)
Tumor Necrosis Factor alpha (TNF α)