The aim: to evaluate combined microscopy techniques for determining the morphological and optical properties of methadone hydrochloride (MDN) crystals. Materials and methods: MDN crystal formation was optimized using a closed container method and crystals were characterized using polarized light microscope (PLM), scanning electron microscopy (SEM) and confocal microscopy (CM). SEM and CM were used to determine MDN crystal thickness and study its relationship with crystal retardation colours using the Michel-Levy Birefringence approach. Results: Dimensions (mean±SD) of diamond shaped MDN crystals were confirmed using SEM and CM. Crystals were 46.4±15.2 Vs 32.0±8.3 µm long, 28.03±8.2 Vs 20.85±5.5 µm wide, and 6.62±2.9 Vs 9.6±4.6 µm thick, respectively. There were significant differences between SEM and CM thickness measurements (U=1283, p<0.05), as the SEM exhibited thinner diamond crystals. The combined use of PLM and Michel-Levy chart enabled the observation of a predominantly yellow coloured MDN crystal, mean thickness at (428 nm) mean retardation value. Conclusion: The SEM was superior and successfully determined MDN crystal dimensions for the first time, whilst the CM results were affected by the Rhodamine dye staining process used for visualisation. The qualitative analysis of the crystallinity status of methadone hydrochloride optimally achieved using a combination of PLM and SEM techniques
In this study new derivatives of O-[2-{''2-Substituted Aryl (''1,''3,''4 thiadiazolyl) ['3,'4-b]-'1,'2,'4- Triazolyl]-Ethyl]-p- chlorobenzald oxime (6-11)have been synthesized from the starting material p-chloro – E- benzaldoxime 1.Compound 2 was synthesized by the reaction of p-chloro – E- benzaldoxime with ethyl acrylate in basic medium. Refluxing compound 2 with hydrazine hydrate in ethanol absolute afforded 3. Derivative 4 was prepared by the reaction of 3 with carbon disulphide, treated of compound 4 with hydrazine hydrate gave 5. The derivatives (6-11) were prepared by the reaction of 5 with different substitutesof aromatic acids. The structures of these compounds were characterized from their melting points, infrared spectroscopy
... Show MoreCalculation of the power density of the nuclear fusion reactions plays an important role in the construction of any power plants. It is clear that the power released by fusion reaction strongly depended on the fusion cross section and fusion reactivity. Our calculation concentrates on the most useful and famous fuels (Deuterium-tritium) since it represents the principle fuels in any large scale system like the so called tokomak.
The purpose of this research is to introduce a concept of general partial metric spaces as a generalization of partial metric space. Give some results and properties and find relations between general partial metric space, partial metric spaces and D-metric spaces.
Praise be to God, and may blessings and peace be upon our master and Prophet Muhammad and those who follow him, and may God be pleased with him
Taha is my guardian and whoever follows their path until the Day of Judgment. And after... The book (The Treasure in the Ten Recitations), written by Abu Muhammad Abdullah bin Abd al-Wasiti, who died in the year 710 AH, is considered one of the important books in recitations: because it included the universal custom that it contained in the books Al-Taysir by Al-Dani and Al-Irshad by Al-Falanisi, as the first of them was specialized.
Satisfy the second with the ten readings
May God bless my time, through His grace and generosity, to achieve this treasure and to publish it
... Show MoreAlzheimer’s Disease (AD) is the most prevailing type of dementia. The prevalence of AD is estimated to be around 5% after 65 years old and is staggering 30% for more than 85 years old in developed countries. AD destroys brain cells causing people to lose their memory, mental functions and ability to continue daily activities. The findings of this study are likely to aid specialists in their decision-making process by using patients’ Magnetic Resonance Imaging (MRI) to distinguish patients with AD from Normal Control (NC). Performance evolution was applied to 346 Magnetic Resonance images from the Alzheimer's Neuroimaging Initiative (ADNI) collection. The Deep Belief Network (DBN) classifier was used to fulfill classification f
... Show MoreThe purpose of this paper is to extend some results concerning generalized derivations to generalized semiderivations of 3-prime near rings.
Merging images is one of the most important technologies in remote sensing applications and geographic information systems. In this study, a simulation process using a camera for fused images by using resizing image for interpolation methods (nearest, bilinear and bicubic). Statistical techniques have been used as an efficient merging technique in the images integration process employing different models namely Local Mean Matching (LMM) and Regression Variable Substitution (RVS), and apply spatial frequency techniques include high pass filter additive method (HPFA). Thus, in the current research, statistical measures have been used to check the quality of the merged images. This has been carried out by calculating the correlation a
... Show MoreThe study aimed to assess the frequency of invasive fungal infection in patients with respiratory diseases by conventional and molecular methods. This study included 117 Broncho alveolar lavage (BAL) samples were collected from patients with respiratory disease (79 male and 38 female) with ages ranged between (20-80) years, who attended Medicine Baghdad Teaching hospital and AL-Emamain AL-Khadhymian Medical City, during the period from September 2019 to April 2020. The results in PCR versus culture methods in this study showed that out of 117 samples of fungal infections 30(25.6 %) were detected by culture method, while the 24(20.5%) samples were detected by PCR technique, the most commonly diagnosed pathogenic fungi is Candida spp.
... Show MoreReal life scheduling problems require the decision maker to consider a number of criteria before arriving at any decision. In this paper, we consider the multi-criteria scheduling problem of n jobs on single machine to minimize a function of five criteria denoted by total completion times (∑), total tardiness (∑), total earliness (∑), maximum tardiness () and maximum earliness (). The single machine total tardiness problem and total earliness problem are already NP-hard, so the considered problem is strongly NP-hard.
We apply two local search algorithms (LSAs) descent method (DM) and simulated annealing method (SM) for the 1// (∑∑∑
... Show MoreThis paper develop conventional Runge-Kutta methods of order four and order five to solve ordinary differential equations with oscillating solutions. The new modified Runge-Kutta methods (MRK) contain the invalidation of phase lag, phase lag’s derivatives, and ampliï¬cation error. Numerical tests from their outcomes show the robustness and competence of the new methods compared to the well-known Runge-Kutta methods in the scientiï¬c literature.